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The authors would like to thank Ph. Peng Xia for his help on statistics analysis. You can also search for this author in PubMed Google Scholar. XT and YL conceptualized the manuscript. Here you will find the basic information on CF. Please call us at if you have further questions. Cystic fibrosis CF is one of the most common inherited diseases in the Caucasian population. It is caused by a failure of a protein that maintains the chloride salt balance in the body.
CF causes the body to produce thick, sticky mucus that can cause breathing problems and lung infections, digestive problems difficulty absorbing some types of foods , and infertility. CF does not cause mental retardation or birth defects. The symptoms of CF may vary from person to person. Some health problems caused by CF can be treated, but the disease itself cannot be cured. Most people with CF have a shortened life span; some will not survive past early childhood, but others will live into their 40s or longer.
Cystic fibrois is caused by an altered gene that a person inherits from his or her parents. CF is inherited in a recessive manner, which means both parents must be carriers to have an affected child. A CF carrier will not have CF-related health problems but may have children with cystic fibrosis if his or her partner is also a CF carrier. Cystic fibrosis is found in all ethnic groups, but is most common in Caucasians. The carrier frequency of the several ethnic groups is shown below.
In the U. There are more than 1, known mutations of the disease. People with only one copy of the defective CF gene are called carriers , and they do not have the disease. Each time two CF carriers have a child, the chances are:. Life expectancy has increased substantially in the last 20 years, rising from age 31 in to age 44 in As of , the U. Cystic fibrosis is most common among Caucasians.
As early as , writings suggested that there were children who likely had CF. He is bewitched and soon must die. In the s, doctors in Switzerland the U. Bacteria that are not harmful to one person with cystic fibrosis can be quite dangerous to another.
Until recently, most people with cystic fibrosis never made it to adulthood. In , the predicted median survival was about 10 years. Lifestyle and environmental factors may play a role in disease progression. Keep reading: Cystic fibrosis ».
This guide provides key questions to ask if your child has cystic fibrosis. Learn more. As kids and teens with cystic fibrosis get older, they may want more independence when it comes to managing their health. Explore seven tips that may help ease the challenges of caring for a child with cystic fibrosis.
Different cystic fibrosis treatments may be available depending on the genes that caused your condition. Health Conditions Discover Plan Connect. Prevalence Diagnosis Risk factors Types of gene mutations Cost Other facts Survival rate Understanding cystic fibrosis Cystic fibrosis is an uncommon genetic disorder.
How common is cystic fibrosis? When are you likely to be diagnosed? Share on Pinterest. What gene mutations are possible?
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